High dose p-5-p Vitamin B6 Supplement
A high dose Vitamin B6 supplement primarily utilised to help reduce elevated prolactin that can come with androgenic PED use. Because P-5-P (pyridoxal 5'-phosphate) is a pre-methylated form of Vitamin B6, this avoids burdening your liver with the methylation conversion process, a vital consideration when consuming doses this high.
150mg per capsules, 120 Capsules
150mg per capsules, 120 Capsules
THE STROM "P-5-P" FORMULA
- Pyridoxal-5'-phosphate [Vitamin B6] (150mg)
120 capsules, 120 serves.
Preventing b6 defeciency is important
"Vitamin B6 in coenzyme forms performs a wide variety of functions in the body and is extremely versatile, with involvement in more than 100 enzyme reactions, mostly concerned with protein metabolism. Both PLP and PMP are involved in amino acid metabolism, and PLP is also involved in the metabolism of one-carbon units, carbohydrates, and lipids. Vitamin B6 also plays a role in cognitive development through the biosynthesis of neurotransmitters and in maintaining normal levels of homocysteine, an amino acid in the blood. Vitamin B6 is involved in gluconeogenesis and glycogenolysis, immune function (for example, it promotes lymphocyte and interleukin-2 production), and hemoglobin formation." - National Institutes for Health
Supplementing with P-5-P is also used to prevent deficiency which can occur when eating restrictive diets or simply nutrient deficient foods with inadequate B6 due to industrial farming practices or the storage of foods before consumption. Simple examples:
With the standard modern lifestyle we also engage in many activities that can upregulate B6 demand and reduce nutritional uptake. These include:
Supplementing with P-5-P is also used to prevent deficiency which can occur when eating restrictive diets or simply nutrient deficient foods with inadequate B6 due to industrial farming practices or the storage of foods before consumption. Simple examples:
- Beef is a primary source of B6 for western cultures, however however-fed beef contains significantly less B6 than grass-fed beef. Additionally, the cuts of beef containing highest B6 content are generally organ meets such as the liver. Historically it was more common to eat organ meats, of which is now very uncommon and hence decreasing beef associated b6 intake.
- Another primary source of B6 is in fortified foods, such as common cereals, bread, and yogurt. With the increase of highly restrictive diets, many of these fortified foods will be excluded, leaving nutrient deficient non-fortified foods.
- Food that is transported long distances to reach the final consumer will often be harvested early, and have long storage times. For example legumes such as beans are good sources of B vitamins, however storage can reduce content significantly compared to freshly harvested.
With the standard modern lifestyle we also engage in many activities that can upregulate B6 demand and reduce nutritional uptake. These include:
- Alcohol consumption decreases the methylation capacity of the liver, decreasing conversion of pyridoxamine (b6) to the active methylated form P-5-P;
- PED's that impair liver function or apply methylation load will also decrease b6 methylation to P-5-P;.
- Damaged stomach lining from chronic neglect of gut health can impair B6 absorption;
- A number of medications will decrease uptake or increase breakdown, some of these include:
- Corticosteroids such as prednisone;
- Broad spectrum antibiotics such as Cycloserine;
- Theophylline used in asthma inhalers;
- Antiepileptic medications including valproic acid, carbamazepine, and phenytoin.
HOW P-5-P (B6) Supports dopamine synthesis
More information coming...
HOW P-5-P (B6) decreases circulating prolactin
More information coming...
HOW P-5-P (B6) SUPPORTS OTHER NUTRIENTS
More information coming...