SupportMAX OCS is our premium all in one On-Cycle-Support product designed to reduce the health harm and risks of PED use. Formulated in 2017 in partnership with Dave Crossland, it has been a mainstay of amateur and professional bodybuilding ever since.
Can be taken in Contest Prep or Off-Season. SupportMAX OCS is for both during the high load periods of your cycle, but also recovering health functions during low load periods.
Can be taken in Contest Prep or Off-Season. SupportMAX OCS is for both during the high load periods of your cycle, but also recovering health functions during low load periods.
While SupportMAX OCS was originally designed to help manage the health complications of PED assisted sports, it can be used by anyone looking to support their health in the same manner. Informed by quantitative data in the form of blood analysis and blood pressure measurement, we've seen the success of SupportMAX OCS in countless athletes and non-athletes alike.
When Richard and Dave Crossland were first working on the formula in 2017, the key concerns they were trying to maintain normal healthy range lipids, blood pressure, liver enzymes (reflecting oxidative stress and bile flow), digestive capability and nutritional uptake. These are specific challenges that arise with PED use, however are also common to many natural athletes due to the extraordinary strain put on the body in high-level sporting.
At Strom we always want an evidence based methodology to our supplementation. Because the issues of concern can so easily be measured with blood analysis and weekly blood pressure measurement - we strongly encourage you do so both prior and during use of SupportMAX OCS. This will allow you to measure the progress you're making.
When Richard and Dave Crossland were first working on the formula in 2017, the key concerns they were trying to maintain normal healthy range lipids, blood pressure, liver enzymes (reflecting oxidative stress and bile flow), digestive capability and nutritional uptake. These are specific challenges that arise with PED use, however are also common to many natural athletes due to the extraordinary strain put on the body in high-level sporting.
At Strom we always want an evidence based methodology to our supplementation. Because the issues of concern can so easily be measured with blood analysis and weekly blood pressure measurement - we strongly encourage you do so both prior and during use of SupportMAX OCS. This will allow you to measure the progress you're making.
THE FORMULA
Each tub of SupportMAX OCS includes 30 servings, available in capsule form.
Each serve (4 capsules) includes the following:
This is not a product designed to treat or cure disease. SupportMAX exists to provide targeted nutritional support for individuals placing significant demands on their physiological systems—whether through intensive training, dietary extremes, PED use, or other stressors that may challenge normal organ function.
Each serve (4 capsules) includes the following:
- N-Acetyl-L-Cysteine (NAC) (1000mg)
- Citrus Bergamot (500mg)
- Betaine HCL (500mg)
- TUDCA (250mg)
- Co-Enzyme Q10 (100mg)
- Hawthorn Berry (100mg)
- Dandelion Root Extract (100mg)
- Vitamin D (5000IU / 1250% RI)
- Magnesium (40mg / 10% RI)
- Selenium (100mcg / 142% RI)
This is not a product designed to treat or cure disease. SupportMAX exists to provide targeted nutritional support for individuals placing significant demands on their physiological systems—whether through intensive training, dietary extremes, PED use, or other stressors that may challenge normal organ function.
N-Acetyl-L-Cysteine (NAC) – 1000mg
NAC is one of the foundations of this formula and a primary fuel for of liver protective and general antioxidant activity. As a precursor to glutathione, NAC provides the first rate-limiting substrate (Cysteine) for cellular defence against oxidative stress.
Glutathione operates as a crucial defence mechanism against reactive oxygen species (ROS) and reactive nitrogen species. When liver stress increases, glutathione reserves become depleted, leaving cells vulnerable to oxidative damage. NAC supplementation replenishes cysteine pools, supporting glutathione synthesis when the body needs it most. It is well-established as the standard clinical treatment for acetaminophen (paracetamol) overdose precisely because of its ability to rapidly restore glutathione levels and protect liver cells from acute toxicity. [2]
Beyond liver, NAC functions as a direct scavenger of free radicals and supports detoxification pathways throughout the body. NAC's also has some anti-inflammatory activity which works through inhibition of NF-κB activation and neurokinin A production, resulting in reduced interleukin-6 (IL-6) levels. This helps reduce chronic inflammatory factors that are ever-present and in excess in modern life.
NAC to Breakdown Sticky Mucus
Before understanding NAC was a glutathione precursor, it was originally introduced clinically as a mucolytic; a compound that breaks down and thins mucus. This property has important implications for respiratory health, particularly during periods where airway function may be compromised.
Airway mucus is an adhesive gel whose biophysical properties are largely determined by entanglements of long gel-forming mucins, primarily MUC5AC and MUC5B. These large glycoprotein molecules are held together by extensive disulfide bond cross-linking, which gives mucus its characteristic thick, viscous consistency.
NAC's mucolytic activity stems from its ability to break these disulfide bonds in heavily cross-linked mucus glycoproteins. [3] This means greater turnover of mucus for more effective clearance of bacteria build up that occurs during respiratory infections. Clear the sickness faster to reduce damage and get well faster.
Glutathione operates as a crucial defence mechanism against reactive oxygen species (ROS) and reactive nitrogen species. When liver stress increases, glutathione reserves become depleted, leaving cells vulnerable to oxidative damage. NAC supplementation replenishes cysteine pools, supporting glutathione synthesis when the body needs it most. It is well-established as the standard clinical treatment for acetaminophen (paracetamol) overdose precisely because of its ability to rapidly restore glutathione levels and protect liver cells from acute toxicity. [2]
Beyond liver, NAC functions as a direct scavenger of free radicals and supports detoxification pathways throughout the body. NAC's also has some anti-inflammatory activity which works through inhibition of NF-κB activation and neurokinin A production, resulting in reduced interleukin-6 (IL-6) levels. This helps reduce chronic inflammatory factors that are ever-present and in excess in modern life.
NAC to Breakdown Sticky Mucus
Before understanding NAC was a glutathione precursor, it was originally introduced clinically as a mucolytic; a compound that breaks down and thins mucus. This property has important implications for respiratory health, particularly during periods where airway function may be compromised.
Airway mucus is an adhesive gel whose biophysical properties are largely determined by entanglements of long gel-forming mucins, primarily MUC5AC and MUC5B. These large glycoprotein molecules are held together by extensive disulfide bond cross-linking, which gives mucus its characteristic thick, viscous consistency.
NAC's mucolytic activity stems from its ability to break these disulfide bonds in heavily cross-linked mucus glycoproteins. [3] This means greater turnover of mucus for more effective clearance of bacteria build up that occurs during respiratory infections. Clear the sickness faster to reduce damage and get well faster.
Citrus Bergamot – 500mg
Citrus bergamot is a fruiting tree primarily cultivated in a small coastal region of Italy, commonly regarded as a cross species of citrus aurantium (bitter orange) and citrus limon (lemon). While it produces many of the same flavonoids as these other citrus fruits—naringin, neohesperidin, and neoeriocitrin—what makes bergamot unique is their significantly higher concentration, plus the presence of two molecules identified as 3-hydroxy-3-methylglutaric acid (HMG) conjugates: brutieridin and melitidin.
Bergamot Contains Statin-Like CompoundsBoth brutieridin and melitidin have the HMG molecules built into them, with documented actions inhibiting HMG-CoA reductase—the same enzyme targeted by prescription statin medications. This is now considered a general consensus in the research literature. Statins work by competitively binding to HMG-CoA reductase, inhibiting the first and rate-limiting step of cholesterol synthesis. Because most circulating cholesterol comes from synthesis rather than diet, this significantly decreases total cholesterol while triggering a cascade that increases LDL receptor expression, shuttling more LDL for processing into bile salts.
Do we see the same side effects as statins?
Not as of yet. Part of this relates to potency—pharmaceutical statins have far greater binding affinity to HMG-CoA reductase. While bergamot can achieve similar lipid modulation outcomes as statins, it is not purely through its statin-like mechanisms, and this is likely why it doesn't come with the same side effect profile.
Bergamot Increases Bile Acid Excretion
When subjects consume citrus bergamot extracts, the amount of bile acids and cholesterol absorbed through the intestine is reduced and excreted in stool. Naringin is a primary compound with this demonstrated effect. The conversion of cholesterol to bile acids accounts for approximately 50% of daily cholesterol excretion. By increasing bile acid excretion, bergamot upregulates the conversion of liver cholesterol to bile acids, decreasing liver cholesterol content and stimulating LDL receptor expression—having a net effect of lowering blood cholesterol levels.
Bergamot Improves Antioxidant ActivityNaringin has demonstrated actions in stimulating superoxide dismutase (SOD), catalase, and glutathione reductase (GR), leading to a reduction in reactive oxygen species in the liver—an attributable factor to decreased lipid oxidation.
A double-blind, placebo-controlled randomised clinical trial demonstrated that bergamot-based nutraceutical supplementation produced significant reductions in total cholesterol (14.6%), LDL-cholesterol (19.9%), non-HDL cholesterol (22.1%), triglycerides (13.1%), and Apolipoprotein B (16%). Additionally, fasting plasma glucose and liver enzymes (GOT, GPT, and γ-GT) showed significant improvements. [DOI: 10.5114/aoms/152791]
A combined in vitro and clinical study further elucidated the mechanisms, demonstrating that bergamot extract stimulates phosphorylation of AMP-activated protein kinase (AMPK) at threonine 172, significantly reducing both cholesterol and triglyceride intracellular content while impairing expression of lipid synthesis-related genes including SREBF1c, SREBF2, ACACA, SCD1, HMGCR, and FASN. [DOI: 10.1002/ptr.7897]
These complementary antioxidant and bile excretion actions, alongside the mild statin-like activity, create an additive effect that allows for total lipid modulation similar to normal statin dosages, but with lesser HMG-CoA reductase-related side effects. This makes bergamot particularly valuable within an on-cycle support formula.
For those requiring more intensive lipid support, SupportMAX OCS stacks well with LipidMAX, which provides 500mg citrus bergamot alongside high-dose lysine (5000mg), vitamin C (1000mg), grapeseed extract (500mg), and CoQ10 (250mg) following the Pauling Protocol approach to arterial health.
Bergamot Contains Statin-Like CompoundsBoth brutieridin and melitidin have the HMG molecules built into them, with documented actions inhibiting HMG-CoA reductase—the same enzyme targeted by prescription statin medications. This is now considered a general consensus in the research literature. Statins work by competitively binding to HMG-CoA reductase, inhibiting the first and rate-limiting step of cholesterol synthesis. Because most circulating cholesterol comes from synthesis rather than diet, this significantly decreases total cholesterol while triggering a cascade that increases LDL receptor expression, shuttling more LDL for processing into bile salts.
Do we see the same side effects as statins?
Not as of yet. Part of this relates to potency—pharmaceutical statins have far greater binding affinity to HMG-CoA reductase. While bergamot can achieve similar lipid modulation outcomes as statins, it is not purely through its statin-like mechanisms, and this is likely why it doesn't come with the same side effect profile.
Bergamot Increases Bile Acid Excretion
When subjects consume citrus bergamot extracts, the amount of bile acids and cholesterol absorbed through the intestine is reduced and excreted in stool. Naringin is a primary compound with this demonstrated effect. The conversion of cholesterol to bile acids accounts for approximately 50% of daily cholesterol excretion. By increasing bile acid excretion, bergamot upregulates the conversion of liver cholesterol to bile acids, decreasing liver cholesterol content and stimulating LDL receptor expression—having a net effect of lowering blood cholesterol levels.
Bergamot Improves Antioxidant ActivityNaringin has demonstrated actions in stimulating superoxide dismutase (SOD), catalase, and glutathione reductase (GR), leading to a reduction in reactive oxygen species in the liver—an attributable factor to decreased lipid oxidation.
A double-blind, placebo-controlled randomised clinical trial demonstrated that bergamot-based nutraceutical supplementation produced significant reductions in total cholesterol (14.6%), LDL-cholesterol (19.9%), non-HDL cholesterol (22.1%), triglycerides (13.1%), and Apolipoprotein B (16%). Additionally, fasting plasma glucose and liver enzymes (GOT, GPT, and γ-GT) showed significant improvements. [DOI: 10.5114/aoms/152791]
A combined in vitro and clinical study further elucidated the mechanisms, demonstrating that bergamot extract stimulates phosphorylation of AMP-activated protein kinase (AMPK) at threonine 172, significantly reducing both cholesterol and triglyceride intracellular content while impairing expression of lipid synthesis-related genes including SREBF1c, SREBF2, ACACA, SCD1, HMGCR, and FASN. [DOI: 10.1002/ptr.7897]
These complementary antioxidant and bile excretion actions, alongside the mild statin-like activity, create an additive effect that allows for total lipid modulation similar to normal statin dosages, but with lesser HMG-CoA reductase-related side effects. This makes bergamot particularly valuable within an on-cycle support formula.
For those requiring more intensive lipid support, SupportMAX OCS stacks well with LipidMAX, which provides 500mg citrus bergamot alongside high-dose lysine (5000mg), vitamin C (1000mg), grapeseed extract (500mg), and CoQ10 (250mg) following the Pauling Protocol approach to arterial health.
Betaine HCL – 500mg
Betaine (trimethylglycine) functions as a methyl donor in one-carbon metabolism, playing essential roles in liver function, homocysteine regulation, and cellular methylation reactions.
Within the liver, betaine serves as a substrate for betaine-homocysteine methyltransferase (BHMT), an enzyme that converts homocysteine back to methionine. Elevated homocysteine is associated with cardiovascular risk and indicates impaired methylation capacity. By supporting homocysteine remethylation, betaine helps maintain healthy methylation status and reduces potential cardiovascular burden.
Betaine also acts as an osmolyte, protecting cells against osmotic stress by regulating intracellular water balance. This osmoprotective function is particularly important in hepatocytes, where metabolic activity can create significant osmotic challenges.
Research examining methyl donor metabolism has confirmed the importance of adequate betaine intake for hepatic phosphatidylcholine synthesis, supporting the export of triglycerides from the liver via very-low-density lipoproteins (VLDL). Inadequate methyl group supply may contribute to hepatic triglyceride accumulation and compromised liver function. [DOI: 10.3168/jds.2019-17319]
The hydrochloride form (Betaine HCL) additionally provides support for gastric acid production, which can be beneficial for protein digestion and mineral absorption—considerations relevant to athletes consuming high-protein diets.
Within the liver, betaine serves as a substrate for betaine-homocysteine methyltransferase (BHMT), an enzyme that converts homocysteine back to methionine. Elevated homocysteine is associated with cardiovascular risk and indicates impaired methylation capacity. By supporting homocysteine remethylation, betaine helps maintain healthy methylation status and reduces potential cardiovascular burden.
Betaine also acts as an osmolyte, protecting cells against osmotic stress by regulating intracellular water balance. This osmoprotective function is particularly important in hepatocytes, where metabolic activity can create significant osmotic challenges.
Research examining methyl donor metabolism has confirmed the importance of adequate betaine intake for hepatic phosphatidylcholine synthesis, supporting the export of triglycerides from the liver via very-low-density lipoproteins (VLDL). Inadequate methyl group supply may contribute to hepatic triglyceride accumulation and compromised liver function. [DOI: 10.3168/jds.2019-17319]
The hydrochloride form (Betaine HCL) additionally provides support for gastric acid production, which can be beneficial for protein digestion and mineral absorption—considerations relevant to athletes consuming high-protein diets.
Co-Enzyme Q10 (CoQ10) – 100mg
CoQ10 is a naturally occurring compound, similar to vitamin K in its chemical structure, but not considered a vitamin because it is synthesised in the body. In fact, CoQ10 is made in every tissue of the body due to its critical role in facilitating the mitochondrial electron transport chain—so everywhere you find mitochondria, you'll find CoQ10. Over 40% of total stores in the human body are estimated to be localised in the mitochondrial inner membrane.
The other key role CoQ10 plays is as a general antioxidant buffer throughout tissues, either regenerating other antioxidants or acting directly. As such, it has follow-on effects in protecting stability, fluidity, and permeability of cell membranes, stimulating cell growth, and inhibiting cell death. The oxidised state of CoQ10 is known as ubiquinone, and the reduced form as ubiquinol.
Why Supplement With CoQ10?If CoQ10 is so ubiquitously present and produced in the body, why supplement with an additional source? The answer lies in pathological conditions: the human body cannot synthesise sufficient amounts of CoQ10 in metabolic syndrome, hypertension, diabetes, and dyslipidemia (abnormal amounts of lipids in circulation). This is precisely the use case for on-cycle support, making supplementation with this essential compound sensible.
Additionally, because decreased production of mevalonate occurs with statin-like compounds (including the bergamot in this formula), and mevalonate is a precursor to CoQ10, supplementation helps offset any potential reduction in endogenous synthesis. This is a primary reason for statin side effects in pharmaceutical contexts, known to cause musculoskeletal tissue issues due to their high CoQ10 demands.
CoQ10's Effects on Elevated Lipids. Because CoQ10 has been a focus of research for over three decades, we have an abundance of human clinical trials to draw insight from. A 2022 comprehensive meta-analysis of 50 randomised human clinical trials encompassing 2,794 participants demonstrated a strong effect in decreasing total cholesterol, triglycerides, and LDL, while increasing HDL levels. For context of scale, at a 250mg dose of ubiquinone CoQ10, the mean cholesterol decrease was calculated to be an average of 10%.
Beyond modulating total lipids, CoQ10 supplementation is also shown to reduce markers of oxidative stress in the liver and increase CoQ10 concentrations in LDL and HDL. This means CoQ10 becomes available to reduce oxidised phospholipids carried by the lipoproteins, thereby neutralising their potential to damage arterial walls—the key reason for concern in persons with elevated lipids.
A systematic review of the role of CoQ10 in coronary heart disease noted that the Q-SYMBIO trial demonstrated CoQ10 supplementation in patients with heart failure not only improved functional capacity but also significantly reduced cardiovascular events and mortality. [DOI: 10.1007/s11883-018-0730-1]
The European Food Safety Authority (EFSA) has authorised the health claim that CoQ10 contributes to the maintenance of normal blood pressure (ID 1509, 1721, 1911).
At 100mg daily, SupportMAX provides a clinically meaningful dose for cardiovascular support and antioxidant protection, complementing the bergamot's lipid-modulating effects. For those with significantly elevated lipids confirmed by bloodwork, stacking with LipidMAX provides an additional 250mg CoQ10, bringing total daily intake to 350mg for more intensive support.
The other key role CoQ10 plays is as a general antioxidant buffer throughout tissues, either regenerating other antioxidants or acting directly. As such, it has follow-on effects in protecting stability, fluidity, and permeability of cell membranes, stimulating cell growth, and inhibiting cell death. The oxidised state of CoQ10 is known as ubiquinone, and the reduced form as ubiquinol.
Why Supplement With CoQ10?If CoQ10 is so ubiquitously present and produced in the body, why supplement with an additional source? The answer lies in pathological conditions: the human body cannot synthesise sufficient amounts of CoQ10 in metabolic syndrome, hypertension, diabetes, and dyslipidemia (abnormal amounts of lipids in circulation). This is precisely the use case for on-cycle support, making supplementation with this essential compound sensible.
Additionally, because decreased production of mevalonate occurs with statin-like compounds (including the bergamot in this formula), and mevalonate is a precursor to CoQ10, supplementation helps offset any potential reduction in endogenous synthesis. This is a primary reason for statin side effects in pharmaceutical contexts, known to cause musculoskeletal tissue issues due to their high CoQ10 demands.
CoQ10's Effects on Elevated Lipids. Because CoQ10 has been a focus of research for over three decades, we have an abundance of human clinical trials to draw insight from. A 2022 comprehensive meta-analysis of 50 randomised human clinical trials encompassing 2,794 participants demonstrated a strong effect in decreasing total cholesterol, triglycerides, and LDL, while increasing HDL levels. For context of scale, at a 250mg dose of ubiquinone CoQ10, the mean cholesterol decrease was calculated to be an average of 10%.
Beyond modulating total lipids, CoQ10 supplementation is also shown to reduce markers of oxidative stress in the liver and increase CoQ10 concentrations in LDL and HDL. This means CoQ10 becomes available to reduce oxidised phospholipids carried by the lipoproteins, thereby neutralising their potential to damage arterial walls—the key reason for concern in persons with elevated lipids.
A systematic review of the role of CoQ10 in coronary heart disease noted that the Q-SYMBIO trial demonstrated CoQ10 supplementation in patients with heart failure not only improved functional capacity but also significantly reduced cardiovascular events and mortality. [DOI: 10.1007/s11883-018-0730-1]
The European Food Safety Authority (EFSA) has authorised the health claim that CoQ10 contributes to the maintenance of normal blood pressure (ID 1509, 1721, 1911).
At 100mg daily, SupportMAX provides a clinically meaningful dose for cardiovascular support and antioxidant protection, complementing the bergamot's lipid-modulating effects. For those with significantly elevated lipids confirmed by bloodwork, stacking with LipidMAX provides an additional 250mg CoQ10, bringing total daily intake to 350mg for more intensive support.
TUDCA (Tauroursodeoxycholic Acid) – 250mg
TUDCA is a water-soluble bile acid that has emerged as one of the most powerful hepatoprotective agents available in supplement form. Unlike most bile acids which can be cytotoxic at elevated concentrations, TUDCA exhibits a unique protective profile that makes it invaluable for liver support.
The primary mechanism of TUDCA's hepatoprotective action lies in its ability to inhibit endoplasmic reticulum (ER) stress. When cells are subjected to metabolic stress, the ER—the cellular organelle responsible for protein folding—becomes overwhelmed, triggering the unfolded protein response (UPR). Prolonged ER stress leads to cellular apoptosis and tissue damage. TUDCA acts as a chemical chaperone, stabilising protein folding and reducing the ER stress cascade.
Research demonstrates that TUDCA provides protection against bile acid-induced hepatocyte apoptosis. In perfused liver models, TUDCA was shown to counteract toxic bile acid-induced gene expression changes, including pro-inflammatory and pro-apoptotic pathways, while upregulating pro-proliferative and anti-apoptotic p53 target genes. [DOI: 10.1515/hsz-2019-0204]
A comprehensive review examining TUDCA's effects on adipose tissue and metabolic function confirmed its ability to inhibit ER stress, inflammation, and apoptosis in various tissues. The review concluded that TUDCA has emerged as a potential therapeutic strategy for obesity-related metabolic disorders through its chemical chaperone activity. [DOI: 10.3389/fendo.2023.1090039]
At 250mg daily, SupportMAX provides an effective dose of TUDCA for supporting hepatobiliary function during periods of elevated physiological stress.
The primary mechanism of TUDCA's hepatoprotective action lies in its ability to inhibit endoplasmic reticulum (ER) stress. When cells are subjected to metabolic stress, the ER—the cellular organelle responsible for protein folding—becomes overwhelmed, triggering the unfolded protein response (UPR). Prolonged ER stress leads to cellular apoptosis and tissue damage. TUDCA acts as a chemical chaperone, stabilising protein folding and reducing the ER stress cascade.
Research demonstrates that TUDCA provides protection against bile acid-induced hepatocyte apoptosis. In perfused liver models, TUDCA was shown to counteract toxic bile acid-induced gene expression changes, including pro-inflammatory and pro-apoptotic pathways, while upregulating pro-proliferative and anti-apoptotic p53 target genes. [DOI: 10.1515/hsz-2019-0204]
A comprehensive review examining TUDCA's effects on adipose tissue and metabolic function confirmed its ability to inhibit ER stress, inflammation, and apoptosis in various tissues. The review concluded that TUDCA has emerged as a potential therapeutic strategy for obesity-related metabolic disorders through its chemical chaperone activity. [DOI: 10.3389/fendo.2023.1090039]
At 250mg daily, SupportMAX provides an effective dose of TUDCA for supporting hepatobiliary function during periods of elevated physiological stress.
Dandelion Root Extract – 100mG
Dandelion has been traditionally used for its choleretic (bile-stimulating), diuretic, anti-inflammatory, and hepatoprotective properties.
Dandelion root contains multiple bioactive compounds including sesquiterpene lactones, phenolic acids, and flavonoids that contribute to its diverse physiological effects. The choleretic action supports bile flow, which is essential for fat digestion and elimination of lipophilic waste products from the liver.
Research examining dandelion's hepatoprotective activity against acetaminophen-induced liver injury demonstrated significant protective effects. The extract decreased thiobarbituric acid-reactive substance levels (a marker of lipid peroxidation), prevented the depletion of sulfhydryl groups (indicating glutathione preservation), and reduced the elevation of serum liver enzymes (AST and ALT). The mechanisms involved include scavenger activities against reactive oxygen species and reactive nitrogen species, attributed to the phenolic compound content. [DOI: 10.1089/jmf.2011.0282]
The mild diuretic effect of dandelion—without significant electrolyte depletion—provides additional support for fluid balance and waste elimination.
Dandelion root contains multiple bioactive compounds including sesquiterpene lactones, phenolic acids, and flavonoids that contribute to its diverse physiological effects. The choleretic action supports bile flow, which is essential for fat digestion and elimination of lipophilic waste products from the liver.
Research examining dandelion's hepatoprotective activity against acetaminophen-induced liver injury demonstrated significant protective effects. The extract decreased thiobarbituric acid-reactive substance levels (a marker of lipid peroxidation), prevented the depletion of sulfhydryl groups (indicating glutathione preservation), and reduced the elevation of serum liver enzymes (AST and ALT). The mechanisms involved include scavenger activities against reactive oxygen species and reactive nitrogen species, attributed to the phenolic compound content. [DOI: 10.1089/jmf.2011.0282]
The mild diuretic effect of dandelion—without significant electrolyte depletion—provides additional support for fluid balance and waste elimination.
Hawthorn Berry – 100mg
Hawthorn (Crataegus spp.) has been used for centuries in traditional medicine for cardiovascular support, and modern research has validated many of these traditional applications.
Hawthorn contains a complex mixture of bioactive compounds including oligomeric procyanidins (OPCs), flavonoids, and triterpenic acids. These compounds collectively contribute to hawthorn's cardioprotective profile through multiple mechanisms: positive inotropic effects (strengthening cardiac contractions), improved coronary blood flow, antioxidant activity, and endothelial protection.
A comprehensive review examining hawthorn's vascular protective effects concluded that the active components reduce oxidative stress and inflammation, regulate lipid levels to prevent accumulation, and protect vascular endothelial function. Clinical trials have demonstrated favourable effects on blood lipids, blood pressure, left ventricular ejection fraction, heart rate, and exercise tolerance. [DOI: 10.1039/d3fo01688a]
The mechanisms include protection of endothelial nitric oxide synthesis, inhibition of free cholesterol accumulation in macrophages, and prevention of foam cell formation—key steps in atherosclerotic plaque development. [DOI: 10.1007/s13659-020-00281-x]
Hawthorn contains a complex mixture of bioactive compounds including oligomeric procyanidins (OPCs), flavonoids, and triterpenic acids. These compounds collectively contribute to hawthorn's cardioprotective profile through multiple mechanisms: positive inotropic effects (strengthening cardiac contractions), improved coronary blood flow, antioxidant activity, and endothelial protection.
A comprehensive review examining hawthorn's vascular protective effects concluded that the active components reduce oxidative stress and inflammation, regulate lipid levels to prevent accumulation, and protect vascular endothelial function. Clinical trials have demonstrated favourable effects on blood lipids, blood pressure, left ventricular ejection fraction, heart rate, and exercise tolerance. [DOI: 10.1039/d3fo01688a]
The mechanisms include protection of endothelial nitric oxide synthesis, inhibition of free cholesterol accumulation in macrophages, and prevention of foam cell formation—key steps in atherosclerotic plaque development. [DOI: 10.1007/s13659-020-00281-x]
Micronutrient Support
The formula is completed with essential micronutrients that support the broader physiological systems:
Vitamin D (5000IU / 1250% RI)
Beyond its established role in calcium metabolism and bone health, vitamin D influences hundreds of genes involved in immune function, cellular differentiation, and inflammatory response. The European Food Safety Authority has authorised the claim that vitamin D contributes to normal cell division (ID 153). Deficiency is common, particularly at higher latitudes, making supplementation prudent for most individuals. The 5000IU dose ensure adequacy even in those with low baseline status, which is standard in the modern lifestyle of indoor work during the day.
Selenium (100mcg / 142% RI)
Selenium is an essential trace mineral required for the synthesis of selenoproteins including glutathione peroxidases—enzymes that work alongside glutathione (supported by NAC) to neutralise hydrogen peroxide and lipid hydroperoxides. The European Food Safety Authority has affirmed that selenium is necessary for normal cardiovascular function (ID 280). [EFSA: 10.2903/j.efsa.2009.1220]
Magnesium (40mg / 10% RI)
The modest dose of Magnesium citrate is actuallyu included in the formula as a flow agent to aid manufacturing, however as a nutritional magnesium donor it does provide some function - it just shouldn't be considered a main supply of magnesium. See our MultiMAX, ZMAX or Tri-Magnesium products for greater magnesium input. Magnesium is essential for proper cardiac rhythm, vascular tone, and serves as a cofactor for hundreds of enzymatic reactions throughout the body.
Vitamin D (5000IU / 1250% RI)
Beyond its established role in calcium metabolism and bone health, vitamin D influences hundreds of genes involved in immune function, cellular differentiation, and inflammatory response. The European Food Safety Authority has authorised the claim that vitamin D contributes to normal cell division (ID 153). Deficiency is common, particularly at higher latitudes, making supplementation prudent for most individuals. The 5000IU dose ensure adequacy even in those with low baseline status, which is standard in the modern lifestyle of indoor work during the day.
Selenium (100mcg / 142% RI)
Selenium is an essential trace mineral required for the synthesis of selenoproteins including glutathione peroxidases—enzymes that work alongside glutathione (supported by NAC) to neutralise hydrogen peroxide and lipid hydroperoxides. The European Food Safety Authority has affirmed that selenium is necessary for normal cardiovascular function (ID 280). [EFSA: 10.2903/j.efsa.2009.1220]
Magnesium (40mg / 10% RI)
The modest dose of Magnesium citrate is actuallyu included in the formula as a flow agent to aid manufacturing, however as a nutritional magnesium donor it does provide some function - it just shouldn't be considered a main supply of magnesium. See our MultiMAX, ZMAX or Tri-Magnesium products for greater magnesium input. Magnesium is essential for proper cardiac rhythm, vascular tone, and serves as a cofactor for hundreds of enzymatic reactions throughout the body.
How Should I Take SupportMAX OCS?
Standard dosing: Take 4 capsules daily, spread throughout the day. The capsules can be taken with or without food. Splitting the dose (e.g., 2 capsules in the morning, 2 in the evening) may optimise absorption and maintain more consistent tissue levels.
Duration of use: SupportMAX is designed for continuous use during periods of elevated physiological stress. Consistent daily use for multiple months is recommended for optimal support.
Complementary products:
For comprehensive organ support, SupportMAX OCS is often stacked with other products in the range, in fact it's often regarded as the best foundation from which you then use other tools for more targetted function:
Duration of use: SupportMAX is designed for continuous use during periods of elevated physiological stress. Consistent daily use for multiple months is recommended for optimal support.
Complementary products:
For comprehensive organ support, SupportMAX OCS is often stacked with other products in the range, in fact it's often regarded as the best foundation from which you then use other tools for more targetted function:
- SystolMAX – for additional blood pressure support, particular emphasis on Systolic function
- GlutathioneMAX – for enhanced antioxidant capacity
- TUDCA 500mg - for additional bile flow and fat uptake support
- LipidMAX – for targeted lipid management, particular emphasis on LDL reduction
- ThromboMAX – for cardiovascular and circulatory support including hematocrit reduction
- GlycoMAX - for enhanced blood sugar management and insulin sensitivity
F.A.Q.
Why is SupportMAX called "OCS"?
OCS stands for "On-Cycle Support"—a term from the bodybuilding community referring to supplementation used during periods of intensive training and elevated physiological stress. While the product was originally designed with this population in mind, the formula provides comprehensive organ support applicable to anyone placing significant demands on their body.
Can I take SupportMAX OCS with other medications?
If you are taking any prescription medications, very importantly those affecting liver function, blood pressure, or blood clotting, consult your healthcare provider before use. This is the same for any supplement.
Should I take SupportMAX OCS with food?
Yes, it is specifically designed to take alongside foods. The hydrochloric acid from Betaine HCl is specifically helpful for digestion of food by providing additional acidity, particularly good for those on high food volume. This is a well established method to reduce acid reflux due to poorly digested food. TUDCA also facilitates the uptake of fats from your meals, ensuring proper absorption - so is another ingredient who's function is dependant on it being present in the digestive tract at the same time as the food. Regarding absorption; the fat-soluble components (CoQ10, Vitamin D) are better absorbed with dietary fat. The water-soluble components (NAC, TUDCA) absorb well regardless of food intake. Our recommended use is to take a total of 4 capsules with meals spread evenly throughout the day. Some larger athletes or those with very high health demands choose to double this dose.
How long before I notice effects?
SupportMAX is designed for ongoing protection rather than acute, noticeable effects. The benefits accumulate over time through consistent use. Most users report a general sense of wellbeing and improved recovery, but the primary value lies in the protective support that may not produce obvious day-to-day changes. That said, if you take bloodwork measurements of liver function and cholesterol we do expect to see improvements in number within 2 months of consistent use - this providing insight into changes that you may not notice on a day-to-day basis.
Can women use SupportMAX OCS?
Absolutely. The formula contains no hormone-specific ingredients and provides general organ support suitable for both men and women seeking liver protective, cardiovascular, and antioxidant benefits.
OCS stands for "On-Cycle Support"—a term from the bodybuilding community referring to supplementation used during periods of intensive training and elevated physiological stress. While the product was originally designed with this population in mind, the formula provides comprehensive organ support applicable to anyone placing significant demands on their body.
Can I take SupportMAX OCS with other medications?
If you are taking any prescription medications, very importantly those affecting liver function, blood pressure, or blood clotting, consult your healthcare provider before use. This is the same for any supplement.
Should I take SupportMAX OCS with food?
Yes, it is specifically designed to take alongside foods. The hydrochloric acid from Betaine HCl is specifically helpful for digestion of food by providing additional acidity, particularly good for those on high food volume. This is a well established method to reduce acid reflux due to poorly digested food. TUDCA also facilitates the uptake of fats from your meals, ensuring proper absorption - so is another ingredient who's function is dependant on it being present in the digestive tract at the same time as the food. Regarding absorption; the fat-soluble components (CoQ10, Vitamin D) are better absorbed with dietary fat. The water-soluble components (NAC, TUDCA) absorb well regardless of food intake. Our recommended use is to take a total of 4 capsules with meals spread evenly throughout the day. Some larger athletes or those with very high health demands choose to double this dose.
How long before I notice effects?
SupportMAX is designed for ongoing protection rather than acute, noticeable effects. The benefits accumulate over time through consistent use. Most users report a general sense of wellbeing and improved recovery, but the primary value lies in the protective support that may not produce obvious day-to-day changes. That said, if you take bloodwork measurements of liver function and cholesterol we do expect to see improvements in number within 2 months of consistent use - this providing insight into changes that you may not notice on a day-to-day basis.
Can women use SupportMAX OCS?
Absolutely. The formula contains no hormone-specific ingredients and provides general organ support suitable for both men and women seeking liver protective, cardiovascular, and antioxidant benefits.
Reference Material
[1] Therapeutic Potential of Nutraceuticals against Drug-Induced Liver Injury (2024, Sethi et al.) - Seminars in Liver Disease [DOI: 10.1055/s-0044-1791559]
[2] Natural Products That Protect Against Acetaminophen Hepatotoxicity: A Call for Increased Rigor in Preclinical Studies of Dietary Supplements (2024, Layman et al.) - Journal of Dietary Supplements [DOI: 10.1080/19390211.2024.2335573]
[3] N-Acetylcysteine as an antioxidant and disulphide breaking agent: the reasons why (2018, Aldini et al.) - Free Radical Research [DOI: 10.1080/10715762.2018.1468564]
[4] Tauroursodeoxycholate protects from glycochenodeoxycholate-induced gene expression changes in perfused rat liver (2019, Paluschinski et al.) - Biological Chemistry [DOI: 10.1515/hsz-2019-0204]
[5] Insights by which TUDCA is a potential therapy against adiposity (2023, Freitas et al.) - Frontiers in Endocrinology [DOI: 10.3389/fendo.2023.1090039]
[6] Comparative effect of a nutraceutical compound based on a flavonoid complex from bergamot on plasma lipids, glucose metabolism, and liver enzymes: a 3-arm, double-blind, placebo-controlled, randomized clinical trial (2022, Fogacci et al.) - Archives of Medical Science [DOI: 10.5114/aoms/152791]
[7] Effect of Citrus bergamia extract on lipid profile: A combined in vitro and human study (2023, Pierdomenico et al.) - Phytotherapy Research [DOI: 10.1002/ptr.7897]
[8] Recent Developments in the Role of Coenzyme Q10 for Coronary Heart Disease: a Systematic Review (2018, Ayers et al.) - Current Atherosclerosis Reports [DOI: 10.1007/s11883-018-0730-1]
[9] Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials (2022, Jorat et al.) [PMID: 36337001]
[10] Statin-like Principles of Bergamot Fruit (Citrus bergamia): Isolation of 3-Hydroxymethylglutaryl Flavonoid Glycosides (2009, Di Donna et al.) - Journal of Natural Products [DOI: 10.1021/np900096w]
[11] On the Inhibitor Effects of Bergamot Juice Flavonoids Binding to the 3-Hydroxy-3-methylglutaryl-CoA Reductase (HMGR) Enzyme (2010, Leopoldini et al.) [PMID: 20843083]
[12] Advances in the study of the vascular protective effects and molecular mechanisms of hawthorn extracts in cardiovascular diseases (2023, Lu et al.) - Food & Function [DOI: 10.1039/d3fo01688a]
[13] Plants Used as Antihypertensive (2020, Verma et al.) - Natural Products and Bioprospecting [DOI: 10.1007/s13659-020-00281-x]
[14] Antioxidant properties of Taraxacum officinale leaf extract are involved in the protective effect against hepatoxicity induced by acetaminophen in mice (2012, Colle et al.) - Journal of Medicinal Food [DOI: 10.1089/jmf.2011.0282]
This content is for educational purposes only and does not intend to cure or diagnose disease, nor make any health claims. There is no intent to slander in any way, but rather produce an informed and accurate third party perspective on the product. Always consult your accredited medical professional before introducing a new supplement. This content is not to be copied or repurposed in any form without express permission from the author.
This article was prepared for stromucation.com. Copyright © 2026
[2] Natural Products That Protect Against Acetaminophen Hepatotoxicity: A Call for Increased Rigor in Preclinical Studies of Dietary Supplements (2024, Layman et al.) - Journal of Dietary Supplements [DOI: 10.1080/19390211.2024.2335573]
[3] N-Acetylcysteine as an antioxidant and disulphide breaking agent: the reasons why (2018, Aldini et al.) - Free Radical Research [DOI: 10.1080/10715762.2018.1468564]
[4] Tauroursodeoxycholate protects from glycochenodeoxycholate-induced gene expression changes in perfused rat liver (2019, Paluschinski et al.) - Biological Chemistry [DOI: 10.1515/hsz-2019-0204]
[5] Insights by which TUDCA is a potential therapy against adiposity (2023, Freitas et al.) - Frontiers in Endocrinology [DOI: 10.3389/fendo.2023.1090039]
[6] Comparative effect of a nutraceutical compound based on a flavonoid complex from bergamot on plasma lipids, glucose metabolism, and liver enzymes: a 3-arm, double-blind, placebo-controlled, randomized clinical trial (2022, Fogacci et al.) - Archives of Medical Science [DOI: 10.5114/aoms/152791]
[7] Effect of Citrus bergamia extract on lipid profile: A combined in vitro and human study (2023, Pierdomenico et al.) - Phytotherapy Research [DOI: 10.1002/ptr.7897]
[8] Recent Developments in the Role of Coenzyme Q10 for Coronary Heart Disease: a Systematic Review (2018, Ayers et al.) - Current Atherosclerosis Reports [DOI: 10.1007/s11883-018-0730-1]
[9] Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials (2022, Jorat et al.) [PMID: 36337001]
[10] Statin-like Principles of Bergamot Fruit (Citrus bergamia): Isolation of 3-Hydroxymethylglutaryl Flavonoid Glycosides (2009, Di Donna et al.) - Journal of Natural Products [DOI: 10.1021/np900096w]
[11] On the Inhibitor Effects of Bergamot Juice Flavonoids Binding to the 3-Hydroxy-3-methylglutaryl-CoA Reductase (HMGR) Enzyme (2010, Leopoldini et al.) [PMID: 20843083]
[12] Advances in the study of the vascular protective effects and molecular mechanisms of hawthorn extracts in cardiovascular diseases (2023, Lu et al.) - Food & Function [DOI: 10.1039/d3fo01688a]
[13] Plants Used as Antihypertensive (2020, Verma et al.) - Natural Products and Bioprospecting [DOI: 10.1007/s13659-020-00281-x]
[14] Antioxidant properties of Taraxacum officinale leaf extract are involved in the protective effect against hepatoxicity induced by acetaminophen in mice (2012, Colle et al.) - Journal of Medicinal Food [DOI: 10.1089/jmf.2011.0282]
This content is for educational purposes only and does not intend to cure or diagnose disease, nor make any health claims. There is no intent to slander in any way, but rather produce an informed and accurate third party perspective on the product. Always consult your accredited medical professional before introducing a new supplement. This content is not to be copied or repurposed in any form without express permission from the author.
This article was prepared for stromucation.com. Copyright © 2026